2023
Spranger Lab demonstrates lymph node microenvironment
suppresses anti-tumor T cells in the lung
February 2, 2023 | Immunity
Read coverage by MIT News
2022
The Spranger lab joins CPCM!
Work from the Vander Heiden lab provides a mechanistic explanation for why hypoxic cancer cells depend on imported lipids for growth
June 23, 2022 | Nature Metabolism
Read coverage by Columbia University Irving Medical Center, BioSpace
Congratulations to CPCM members Mike Yaffe and Michael Hemann on winning a 2022 Bose grant for ambitious ideas!
June 17, 2022
Read coverage by MIT News
CPCM-member Forest White collaborated with KI colleague Tyler Jacks on deciphering the immunopeptidome in vivo to reveal new tumor antigens
June 15, 2022
Manalis Lab study finds that cells take out the trash before they divide
May 10, 2022 | eLife
Read coverage by MIT News
White Lab postdoc and Convergence Scholar Tigist Tamir creates “Edges and Nodes,” a video series aimed at demystifying the life of a scientist
March 2022
2021
Congratulations to Jason Conage-Pough (White lab) and Alicia Darnell (Vander Heiden lab) on receiving the 2021 Peter Karches Mentorship Prize!
November 5, 2021
Yaffe lab research, in collaboration with the Irvine lab, finds that combining chemotherapy, tumor injury, and immunotherapy can re-engage the immune system to destroy tumors in mice
October 19, 2021 | Science Signaling
Read coverage by MIT News
CPCM member Angela Koehler participates in AACR discussion panel on the importance of academia-industry collaboration, “Embracing Entrepreneurship in Cancer Research”
May 20, 2021
Congratulations to CPCM member Matthew Vander Heiden upon being selected as the new Director of MIT’s Koch Institute for Integrative Cancer Research
April 1, 2021
Read coverage by MIT News, Boston Globe, Boston Business Journal, Endpoints News
Research in the Yaffe lab is supporting positive clinical trial data toward better treatment response predictions in prostate cancer
March 11, 2021
Read coverage by KI News
Yaffe Lab finds that MAPKAP kinase-2 drives expression of angiogenic factors by tumor-associated macrophages in a model of inflammattion-induced colon cancer
Feburary 23, 2021 | Frontiers in Immunology
A new mass spectrometry method developed in the White Lab opens up new clinical avenues for personalized treatment based on cell signaling
January 28, 2021 | Cancer Research
Read coverage by KI News
Vander Heiden Lab study sheds light on the longstanding question of why cancer cells get their energy from fermentation
January 15, 2021 | Molecular Cell
Read coverage by MIT News
2020
Koehler Lab identifies a molecule that could target advanced prostate cancer as well as a variety of other cancers
November 19, 2020 | Cell Chemical Biology
Read coverage by MIT News
Hemann Lab establishes that two treatment methods enhance chemotherapy by the same means: cellular senescence (Study 1; Study 2)
November 17, 2020 | PNAS
Read coverage by MIT Biology News
Michael Hemann presents “New Mechanisms for Old Cancer Drugs” as part of the Dana-Farber/Harvard Cancer seminar series
October 1, 2020
The Hemann lab’s inTRINSIC model investigates subtype-specific susceptibilities in glioblastoma
September 16, 2020 | Molecular Systems Biology
The Yaffe Lab presents Transite, a computational approach to identifying RNA-binding proteins
August 25, 2020 | Cell Reports
Read coverage by KI News
The Yaffe Lab and colleagues describe the concept of augmented synthetic lethality which can enhance chemotherapy response
August 17, 2020 | Nature Communications
Read coverage by KI News
Yaffe Lab research shows that BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage
August 14, 2020 | Nature Communications
Read coverage by KI News, Author’s view
Allison Lau and colleagues in the Vander Heiden Lab dissect cell type-specific metabolism in pancreatic ductal adenocarcinoma
July 10, 2020 | eLife
Read coverage by Science in Boston
Manalis lab monitors cell growth efficiency by studying cell size and cell cycle
June 24, 2020 | PNAS
Lauren Stopfer and colleagues from the White and Lauffenburger labs are counting antigens
June 2, 2020 | Nature Communications
Congratulations to Lauren Stopfer (White lab) and Suzy Ramos (Hemann lab) on receiving a 2020 Margaret A. Cunningham Immune Mechanisms in Cancer Research Fellowship Award
April 2020
2019
Matt Vander Heiden in the Spotlight: Understanding cancer metabolism
December 4, 2019
Congratulations to Rob Wilson (Koehler lab) on receiving the 2019 Peter Karches Mentorship Prize!
November 15, 2019
Vander Heiden and Jacks labs join forces to identifya new therapeutic target for small cell lung cancer
November 6, 2019 | Science Translational Medicine
Read coverage by MIT News and on the NIH Director’s blog
Congratulations to Lauren Stopfer (White lab) on her 2020 Siebel Scholar Award for academic achievement and leadership!
September 25, 2019
Read coverage by MIT News
Yaffe lab identifies a new drug combination to kill cancer cells
July 10, 2019 | Cell Systems
Read coverage by MIT News
New study from the Vander Heiden lab on the role of serine availability in tumor growth
June 4, 2019 | Cell Metabolism
Vander Heiden lab and colleagues develop a new method to measure tumor nutrient availability in mice
April 16, 2019 | Elife
Read more: MIT News, KI News and The Atlantic
Koehler lab reports a novel small molecule that attenuates Myc-driven transcription
March 14, 2019 | Cell Chemical Biology
Angela Koehler receives the MIT Junior Bose Award for Teaching Excellence
March 2019
New Yaffe lab study on ROS and oxidative stress in cancer cells
February 20, 2019 | Cell Systems
The Manalis lab joins CPCM!
An insightful essay by CPCM Director Michael Yaffe in Science Signaling
January 22, 2019 | Science Signaling
Read coverage by KI News
2018
Learn more about the Koehler lab array-based ligand discovery platform
2018 | Methods in Enzymology
New study from the Vander Heiden lab on isocitrate dehydrogenase and 2-hydroxyglutarate production
October 30, 2018 | Journal of Biological Chemistry
Congratulations to Shelby Doyle (Koehler lab graduate student) on receiving the 2018 Peter Karches Mentorship Prize!
October 29, 2018
The Vander Heiden lab explores the role of PKM2 in pancreatic cancer
October 23, 2018 | Cancer & Metabolism
CPCM faculty member Angela Koehler reflects on Kendal Square’s rise
October 18, 2018 | MIT Spectrum
Congratulations to Allison Lau (Vander Heiden lab postdoc) on receiving the Koch Institute Stanley (1958) and Bonnie Klein Research Travel Fellowship!
New publication from the Yaffe lab in Cell Systems
September 19, 2018 | Cell Systems
Read more about this work: Cell Systems Preview, KI news
Congratulations to Azucena (Susy) Ramos (Hemann lab MD/PhD student) for receiving the prestigious Ruth L. Kirschstein Award (F31) from the NIH!
Great article about CPCM member Matt Vander Heiden
August 28, 2018 | MIT News
Congratulations to Tatiana Netterfield (Yaffe lab grad student) on being awarded the NSF Graduate Research Fellowship!
Another informative review from the Vander Heiden lab on cancer cell metabolism
August 7, 2018 | Disease Models & Mechanisms
New study from the Vander Heiden lab on the role of aspartate in cancer
June 25, 2018 | Nature Cell Biology
Read coverage by MIT News and Nature News & Views.
Vander Heiden lab and clinical collaborators identify a mechanism for tissue wasting in pancreatic cancer
June 20, 2018 | Nature
Read more about this work: MIT News, Nature News & Views, STAT News
Yaffe/ Floyd/ Hammond lab collaboration: using targeted nanoparticles to fight brain tumors
May 18, 2018 | Nature Communications
Read coverage by MIT News and Nature Nanotechnology News & Views
Nick Struntz (Koehler lab postdoc) awarded MIT-GSK Gertrude B. Elion Fellowship
April 17, 2018 | MIT News
New study from the Yaffe Lab offers novel insight into colon cancer development
April 16, 2018 | PNAS
The Man Who Uncovered a New (Old) Way to Fight Cancer
February 21, 2018 | MIT Technology Review
